top of page
Insect Pathology and Pathogen Genomics Lab.​
National Chung Hsing University
Our research toward to
D A
iversity
ynamic
eepness
pplications
Platform of Insect Pathology
of insect pathogens
provide information to "how" many? and "what" they are?
of insect pathogens
surveillance of beneficial insect diseases would be helpful for predicting "where" are insect pathogens going
of insect pathogens
to optimize the system for pest management
of insect pathology
by using technological advances in omics to establish a better understanding of "how" insect pathogens work in their host
Diversity
Diversity of Insect Pathogens
In Taiwan, insect diversity is high, we believe that there is number of pathogens in Insects waiting for us to uncover. By identifying and characterizing new insect pathogens could provide information to "how many?" and "what they are?" in the insect population. besides, a new microbial for pest control would be found based on these insect pathogens resources.
Previously, we have fully identified and characterized few entomopathogenic bacteria, viruses, and invertebrate microsporidian. Currently, our group have collected numerous diseased insect and these samples were preliminarily identified by light microscope exam and staining methods, some of the diseased insects were also subject to molecular diagnosis. What is next step...
Dynamic
Dynamic of Insect Pathogens
Prevalence of insect pathogens in beneficial insects (i.e., honey bees) is important; surveillance of beneficial insect diseases is needed for the establishment of the database and therefore would be helpful for prediction of insect pathogens dynamics.
Our efforts are focusing on the monitor of serious disease in beneficial insects and improvement of the diagnoses of these pathogens. From 2010, we started to investigate the honey bee microsporidiosis, which causes by Nosema ceranae by developing rapid detection method. Recently, an acute viral disease outbreaks in the population of Eastern honey bees (Apis cerana). A story of dynamic insect pathology is now starting again...
Deepness
Deepness in Insect Pathology
We are interested the comparative genomics, functional genomics and the mechanisms of insect-microbiome interactions; by using technological advances in omics to establish a better understanding of the mechanisms of insect-pathogens interactions. Now, we are focusing on the genes that involved in the host range of nucleopolyhedroviruses (NPVs); besides, the functional genomics in either NPVs and other insect pathogens that have potential to develop as new microbial control agents will be processed. The knowledge about how the insect pathogens pathogenesis and why high virulence they are would support the application of pest management.
Applications
Applications of Insect Pathogens
Our research is expected to reach the final goal of applications. This goal is based on the diversity and dynamic and deepness of insect pathology and to the aim of optimized-systems for pest management, pathogens diagnosis, and biotechnology usage:
(I) By discovering insect pathogens, we could establish the insect microbial database for the selection of potential pest management reagents.
(II) Surveillance and collection of pathogens dynamic information in beneficial insects could improve the current passive management of rearing system.
(III) Deepness research in pathogens and insect host could help us to better understand the virulence factors of these pathogens, and provide the strategy of future genetic modifications.
bottom of page